RELATED: Fallout 4: The 10 Best DLC Weapons If you're on the hunt for a new, powerful weapon, here's where to find the 25 best weapons in Fallout 4. Many of them are in hidden locations or unmarked spots, which necessitates the right skills or even a dash of luck to even stumble across in the first place. However, in true open-world survival game fashion, Fallout 4 doesn't just hand out its best weapons on a silver platter. In the Commonwealth, having the best gear and and best weapons is what ensures one's ability to survive, so having the right tools of destruction is absolutely vital. Without preparation, the Sole Survivor will struggle as they begin their journey to find out what happened to their son Shaun. The wasteland of Fallout 4 is a harsh and dangerous place.